Pub. Date : 2022 Jan 31
PMID : 35102230
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Repeat-associated non-AUG (RAN) translation of mRNAs/transcripts responsible for polyglutamine (polyQ) diseases may generate peptides containing different mono amino acid tracts such as polyserine (polyS) and polyleucine (polyL). | polyleucine | RAN, member RAS oncogene family | Mus musculus |
| 2 | Repeat-associated non-AUG (RAN) translation of mRNAs/transcripts responsible for polyglutamine (polyQ) diseases may generate peptides containing different mono amino acid tracts such as polyserine (polyS) and polyleucine (polyL). | polyleucine | RAN, member RAS oncogene family | Mus musculus |
| 3 | Thus, the RAN translation-related proteins containing polyS and polyL have the potential to propagate and the proteins generated by all polyQ diseases might exert universal toxicity in the recipient cells. | polyleucine | RAN, member RAS oncogene family | Mus musculus |