Pub. Date : 2022
PMID : 35085258
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine treatment regulates PD-L1 and PD-L2 expression via inhibition of Akt pathway in HER2-type breast cancer cells. | Nicotine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | In addition, nicotine treatment decreased the phosphorylation of Akt in SK-BR-3 cells, but not in other cell lines. | Nicotine | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | These results show that nicotine regulates the expression of immune checkpoint molecules, PD-L1 and PD-L2, via inhibition of Akt phosphorylation. | Nicotine | AKT serine/threonine kinase 1 | Homo sapiens |