Title : Nicotine treatment regulates PD-L1 and PD-L2 expression via inhibition of Akt pathway in HER2-type breast cancer cells.

Pub. Date : 2022

PMID : 35085258






3 Functional Relationships(s)
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1 Nicotine treatment regulates PD-L1 and PD-L2 expression via inhibition of Akt pathway in HER2-type breast cancer cells. Nicotine AKT serine/threonine kinase 1 Homo sapiens
2 In addition, nicotine treatment decreased the phosphorylation of Akt in SK-BR-3 cells, but not in other cell lines. Nicotine AKT serine/threonine kinase 1 Homo sapiens
3 These results show that nicotine regulates the expression of immune checkpoint molecules, PD-L1 and PD-L2, via inhibition of Akt phosphorylation. Nicotine AKT serine/threonine kinase 1 Homo sapiens