Title : Bupivacaine reduces GlyT1 expression by potentiating the p-AMPKα/BDNF signalling pathway in spinal astrocytes of rats.

Pub. Date : 2022 Jan 26

PMID : 35082359






2 Functional Relationships(s)
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1 After treatment with bupivacaine, GlyT1 expression was diminished in a concentration-dependent manner, while the expression of BDNF and p-AMPK was increased. Bupivacaine protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus
2 Moreover, 7,8-DHF decreased GlyT1 expression, and AMPK knockdown suppressed the upregulation of BDNF expression by bupivacaine. Bupivacaine protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus