Title : Epoxymicheliolide directly targets histone H2B to inhibit neuroinflammation via recruiting E3 ligase RNF20.

Pub. Date : 2022 Mar

PMID : 35074526






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mechanism study suggests that ECL covalently modifies a previously undisclosed lysine 46 (K46) in H2B, and recruits E3 ubiquitin ligase RNF20 to promote H2Bub1 at K120. Lysine H2B clustered histone 21 Homo sapiens