Pub. Date : 2022 Jun
PMID : 35074264
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Olaparib Use in Patients With Metastatic Breast Cancer Harboring Somatic BRCA1/2 Mutations or Mutations in Non-BRCA1/2, DNA Damage Repair Genes. | olaparib | BRCA1 DNA repair associated | Homo sapiens |
| 2 | Olaparib Use in Patients With Metastatic Breast Cancer Harboring Somatic BRCA1/2 Mutations or Mutations in Non-BRCA1/2, DNA Damage Repair Genes. | olaparib | BRCA1 DNA repair associated | Homo sapiens |
| 3 | This study examines the use of olaparib in patients with metastatic breast cancer harboring sBRCA1/2 or germline or somatic non-BRCA1/2, HRR mutations and demonstrates potential activity of PARPi in this setting. | olaparib | BRCA1 DNA repair associated | Homo sapiens |
| 4 | METHODS: In this retrospective, single institution study, patients who were treated with off-label, off-protocol olaparib for metastatic breast cancer harboring sBRCA1/2 or germline or somatic non-BRCA1/2, HRR mutations were identified. | olaparib | BRCA1 DNA repair associated | Homo sapiens |