Pub. Date : 2021
PMID : 35069549
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Results: Pretreatment with SMS ameliorated MSU-induced acute gouty arthritis in mice with increased PI3K/Akt activation and M2 macrophage polarization in the joint tissues. | sms | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | In vitro, SMS treatment significantly inhibited MSU-triggered inflammatory response, increased p-Akt and Arg-1 expression in macrophages, and promoted M2 macrophage polarization. | sms | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | The anti-inflammatory mechanism of SMS may exert anti-inflammatory effects by promoting M2 polarization via PI3K/Akt signaling. | sms | thymoma viral proto-oncogene 1 | Mus musculus |