Pub. Date : 2022 Feb 26
PMID : 35066375
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | For this effect, ATRA downregulated both protein and enzyme activity levels of DNA methyltransferase 1 and 3b and activated E6AP expression via promoter hypomethylation in HepG2 cells but not in Hep3B cells, in which p53 was absent. | Tretinoin | tumor protein p53 | Homo sapiens |
2 | Ectopic p53 expression but not E6AP overexpression restored the ability of ATRA to downregulate HCV Core levels in Hep3B cells, suggesting a direct role of p53 in the E6AP-mediated ubiquitination of HCV Core. | Tretinoin | tumor protein p53 | Homo sapiens |
3 | Ectopic p53 expression but not E6AP overexpression restored the ability of ATRA to downregulate HCV Core levels in Hep3B cells, suggesting a direct role of p53 in the E6AP-mediated ubiquitination of HCV Core. | Tretinoin | tumor protein p53 | Homo sapiens |