Title : Time-resolved FRET screening identifies small molecular modifiers of mutant Huntingtin conformational inflexibility in patient-derived cells.

Pub. Date : 2022 Jun

PMID : 35058188






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 CAG repeat expansions in mutant Huntingtin (mHTT) exon 1 encode for polyglutamine (polyQ) stretches and influence age of onset and disease severity, depending on their length. polyglutamine huntingtin Homo sapiens
2 CAG repeat expansions in mutant Huntingtin (mHTT) exon 1 encode for polyglutamine (polyQ) stretches and influence age of onset and disease severity, depending on their length. polyglutamine huntingtin Homo sapiens