Title : Syndecan-4 Is a Key Facilitator of the SARS-CoV-2 Delta Variant's Superior Transmission.

Pub. Date : 2022 Jan 12

PMID : 35054983






2 Functional Relationships(s)
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Protein Name
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1 Compared to the wild-type spike, the Delta one shows a higher affinity towards heparan sulfate proteoglycans than towards ACE2. Heparitin Sulfate surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 In addition to attachment to the polyanionic heparan sulfate chains, the Delta spike"s molecular interactions with syndecan-4 also involve syndecan-4"s cell-binding domain that mediates cell-to-cell adhesion. Heparitin Sulfate surface glycoprotein Severe acute respiratory syndrome coronavirus 2