Title : Adenosine A2A Receptor in Bone Marrow-Derived Cells Mediated Macrophages M2 Polarization via PPARĪ³-P65 Pathway in Chronic Hypoperfusion Situation.

Pub. Date : 2021

PMID : 35046793






1 Functional Relationships(s)
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1 Under low-glucose and hypoxic conditions, CGS21680 treatment promoted macrophage M2 polarization, increased the expression of PPARgamma, P65, and interleukin-10 (IL-10) and suppressed the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta). 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine interleukin 1 beta Mus musculus