Title : Bisphenol A-sulfate conjugate disrupts AURKA transcription and cell cycle in BeWo cytotrophoblasts.

Pub. Date : 2022 Apr 5

PMID : 35041905






2 Functional Relationships(s)
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1 BeWo exhibits expression of the genes encoding OATP1A2 and OATP4A1 as known sulfated steroid transporters and STS, suggesting that BPA-S suppresses cell growth activity via the sulfate-sulfatase pathway. bisphenol A arylsulfatase family member H Homo sapiens
2 These results suggested that BPA-S triggers cell cycle arrest and inhibits proliferation of BeWo cytotrophoblasts by decreased AURKA, an effect that is mediated by the sulfate-sulfatase pathway. bisphenol A arylsulfatase family member H Homo sapiens