Title : Binding behavior of spike protein and receptor binding domain of the SARS-CoV-2 virus at different environmental conditions.

Pub. Date : 2022 Jan 17

PMID : 35039570






2 Functional Relationships(s)
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1 The objective of this study is to investigate the effect of temperature, fatty acids, ions, and protein concentration on the binding behavior and rates of association and dissociation between the S protein and RBD of SARS-CoV-2 and the hydrophobic aminopropylsilane (APS) biosensors using biolayer interferometry (BLI) validated with molecular dynamics simulation. aminopropylsilane surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 The objective of this study is to investigate the effect of temperature, fatty acids, ions, and protein concentration on the binding behavior and rates of association and dissociation between the S protein and RBD of SARS-CoV-2 and the hydrophobic aminopropylsilane (APS) biosensors using biolayer interferometry (BLI) validated with molecular dynamics simulation. aminopropylsilane surface glycoprotein Severe acute respiratory syndrome coronavirus 2