Pub. Date : 2022 Jan
PMID : 35017179
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | High-affinity nAChRs can incorporate additional subunits, including beta3, alpha6, or alpha5 subunits, with the resulting nAChR subtypes playing discrete and dissociable roles in the stimulatory actions of nicotine on brain dopamine transmission. | Nicotine | uncharacterized protein LOC107802668 | Nicotiana tabacum |
2 | nAChRs containing alpha3 and beta4 subunits are responsible for the low-affinity nicotine binding sites in the brain and are enriched in brain sites involved in aversion, including the medial habenula, interpeduncular nucleus, and nucleus of the solitary tract, brain sites in which alpha5 nAChR subunits are also expressed. | Nicotine | uncharacterized protein LOC107802668 | Nicotiana tabacum |