Title : Pyrazole as a modifier of liver microsomal monooxygenase in DBA/2N and AKR/J mice.

Pub. Date : 1987 Nov 15

PMID : 3500725






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the D2 mouse pyrazole strongly increases the coumarin 7-hydroxylase (CoH) and 7-ethoxycoumarin O-deethylase (ECDE) activities while on the total cytochrome P-450 (P-450) content and ethylmorphine N-demethylase (EMDM) and benzo(a)pyrene hydroxylase (AHH) activities the effect is biphasic (increased with lower doses and decreased with higher). pyrazole cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus