Pub. Date : 2022 May
PMID : 34988938
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Treatment with BKM120 decreased AtT-20/D16v-F2 cell viability, induced a G0/G1 cell cycle arrest, reduced the phosphorylation of Akt at Serine 473, and increased p27 expression. | NVP-BKM120 | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | CONCLUSION: In vitro inhibition of PI3K/AKT pathway by BKM120 resulted in anti-proliferative effects on corticotroph tumor cells, decreasing cell viability and ACTH production. | NVP-BKM120 | thymoma viral proto-oncogene 1 | Mus musculus |