Title : Inactivating Celsr2 promotes motor axon fasciculation and regeneration in mouse and human.

Pub. Date : 2022 Apr 18

PMID : 34983065






1 Functional Relationships(s)
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1 In mouse adult spinal cord after root avulsion, in mouse embryonic spinal cords, and in cultured human motoneurons, Celsr2 downregulation is accompanied by increased levels of GTP-bound Rac1 and Cdc42, and of JNK and c-Jun. Guanosine Triphosphate Rac family small GTPase 1 Homo sapiens