Pub. Date : 1987
PMID : 3497889
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PGE2 at concentrations ranging from 0.1 to 5.0 ng/ml effectively inhibited or antagonized this enhancing effect of IL-1, with the majority of this IL-1 augmentation abrogated by 5.0 ng/ml PGE2. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 2 | PGE2 at concentrations ranging from 0.1 to 5.0 ng/ml effectively inhibited or antagonized this enhancing effect of IL-1, with the majority of this IL-1 augmentation abrogated by 5.0 ng/ml PGE2. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 3 | PGE2 at concentrations ranging from 0.1 to 5.0 ng/ml effectively inhibited or antagonized this enhancing effect of IL-1, with the majority of this IL-1 augmentation abrogated by 5.0 ng/ml PGE2. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 4 | PGE2 at concentrations ranging from 0.1 to 5.0 ng/ml effectively inhibited or antagonized this enhancing effect of IL-1, with the majority of this IL-1 augmentation abrogated by 5.0 ng/ml PGE2. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 5 | PGE2 was also found to markedly suppress the enhanced production of IL-2 resulting from the addition of IL-1 to Con A stimulated lymphocytes, however, the amount of IL-2 produced in the cultures containing both IL-1 and PGE2 was always greater than that produced in the cultures which contained only PGE2. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 6 | PGE2 was also found to markedly suppress the enhanced production of IL-2 resulting from the addition of IL-1 to Con A stimulated lymphocytes, however, the amount of IL-2 produced in the cultures containing both IL-1 and PGE2 was always greater than that produced in the cultures which contained only PGE2. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 7 | This finding indicates that IL-1 could partially reverse or antagonize the suppressive effect of PGE2 on IL-2 production. | Dinoprostone | interleukin 1 complex | Mus musculus |
| 8 | The addition of IL-1 to these cultured T cells neither altered the response of the culture T cells to IL-2 nor altered the sensitivity of these cells to PGE2. | Dinoprostone | interleukin 1 complex | Mus musculus |