Pub. Date : 2022 Feb
PMID : 34973529
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pharmacological inhibition of TLR4-NF-kappaB signaling by TAK-242 attenuates hydrocephalus after intraventricular hemorrhage. | ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate | toll-like receptor 4 | Rattus norvegicus |
| 2 | We also explore the possible role of TAK-242 for the regulation of TLR4-NF-kappaB signaling pathway. | ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate | toll-like receptor 4 | Rattus norvegicus |
| 3 | The underlying mechanism involved the TAK-242-mediated downregulation of TLR4-NF-kappaB signaling pathway. | ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate | toll-like receptor 4 | Rattus norvegicus |