Title : New Synthetic Caffeine Analogs as Modulators of the Cholinergic System.

Pub. Date : 2022 Mar

PMID : 34969831






1 Functional Relationships(s)
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1 To this end, a theophylline structure was connected to a pyrrolidine structure through a methylene chain of different lengths (3 to 7 carbon atoms) to give compounds 7-11 All caffeine derivatives inhibited the AChE, of which compound 11 showed the strongest effect. Carbon acetylcholinesterase (Cartwright blood group) Homo sapiens