Title : Co-treatment with miR-21-5p inhibitor and Aurora kinase inhibitor reversine suppresses breast cancer progression by targeting sprouty RTK signaling antagonist 2.

Pub. Date : 2022 Jan

PMID : 34967265






2 Functional Relationships(s)
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1 SPRY2, downstream of miR-21-5p, participated in HBC progression with reversine. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine sprouty RTK signaling antagonist 2 Homo sapiens
2 Overall, our study proved that combining the miR-21-5p inhibitor with reversine produced a synergistic effect by regulating SPRY2, thereby limiting HBC progression. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine sprouty RTK signaling antagonist 2 Homo sapiens