Title : FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis.

Pub. Date : 2021 Dec 29

PMID : 34965856






8 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis. Iron ferritin heavy chain 1 Homo sapiens
2 Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. Iron ferritin heavy chain 1 Homo sapiens
3 Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. Iron ferritin heavy chain 1 Homo sapiens
4 Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. Iron ferritin heavy chain 1 Homo sapiens
5 Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. Iron ferritin heavy chain 1 Homo sapiens
6 Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. Iron ferritin heavy chain 1 Homo sapiens
7 Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. Iron ferritin heavy chain 1 Homo sapiens
8 Importantly, the proteins interaction network elucidated that FTH is involved in iron homeostasis maintenance and lysosomal-dependent degradation. Iron ferritin heavy chain 1 Homo sapiens