Pub. Date : 2021 Dec 29
PMID : 34965856
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis. | Iron | ferritin heavy chain 1 | Homo sapiens |
2 | Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. | Iron | ferritin heavy chain 1 | Homo sapiens |
3 | Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. | Iron | ferritin heavy chain 1 | Homo sapiens |
4 | Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. | Iron | ferritin heavy chain 1 | Homo sapiens |
5 | Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. | Iron | ferritin heavy chain 1 | Homo sapiens |
6 | Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. | Iron | ferritin heavy chain 1 | Homo sapiens |
7 | Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated production of ROS. | Iron | ferritin heavy chain 1 | Homo sapiens |
8 | Importantly, the proteins interaction network elucidated that FTH is involved in iron homeostasis maintenance and lysosomal-dependent degradation. | Iron | ferritin heavy chain 1 | Homo sapiens |