Pub. Date : 2021 Nov 25
PMID : 34959778
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Several recent studies have demonstrated that the direct precursor of vitamin D3, the calcifediol (25(OH)D3), through the binding to the nuclear vitamin D receptor (VDR), is able to regulate the expression of many genes involved in several cellular processes. | Calcifediol | vitamin D receptor | Homo sapiens |
| 2 | Several recent studies have demonstrated that the direct precursor of vitamin D3, the calcifediol (25(OH)D3), through the binding to the nuclear vitamin D receptor (VDR), is able to regulate the expression of many genes involved in several cellular processes. | Calcifediol | vitamin D receptor | Homo sapiens |
| 3 | Several recent studies have demonstrated that the direct precursor of vitamin D3, the calcifediol (25(OH)D3), through the binding to the nuclear vitamin D receptor (VDR), is able to regulate the expression of many genes involved in several cellular processes. | Calcifediol | vitamin D receptor | Homo sapiens |
| 4 | Several recent studies have demonstrated that the direct precursor of vitamin D3, the calcifediol (25(OH)D3), through the binding to the nuclear vitamin D receptor (VDR), is able to regulate the expression of many genes involved in several cellular processes. | Calcifediol | vitamin D receptor | Homo sapiens |
| 5 | Considering that itself may function as a VDR ligand, although with a lower affinity, respect than the active form of vitamin D, we have assumed that 25(OH)D3 by binding the VDR could have a vitamin"s D3 activity such as activating non-genomic pathways, and in particular we selected mesenchymal stem cells derived from human adipose tissue (hADMSCs) for the in vitro assessment of the intracellular Ca2+ mobilization in response to 25(OH)D3. | Calcifediol | vitamin D receptor | Homo sapiens |
| 6 | Considering that itself may function as a VDR ligand, although with a lower affinity, respect than the active form of vitamin D, we have assumed that 25(OH)D3 by binding the VDR could have a vitamin"s D3 activity such as activating non-genomic pathways, and in particular we selected mesenchymal stem cells derived from human adipose tissue (hADMSCs) for the in vitro assessment of the intracellular Ca2+ mobilization in response to 25(OH)D3. | Calcifediol | vitamin D receptor | Homo sapiens |