Title : Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression.

Pub. Date : 2021 Dec 7

PMID : 34959389






1 Functional Relationships(s)
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1 The mRNAs encoding HTT, APP and alphaSYN contain an atypical iron response element (IRE) in their 5"-untranslated regions (5"-UTRs) that bind iron regulatory protein 1 (IRP1), and Posiphen specifically bound this complex. Iron huntingtin Homo sapiens