Title : The Conformational State of the BTK Substrate PLCγ Contributes to Ibrutinib Resistance.

Pub. Date : 2022 Mar 15

PMID : 34954235






3 Functional Relationships(s)
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Protein Name
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1 The conformational state of the BTK substrate PLCgamma contributes to Ibrutinib resistance. ibrutinib Bruton tyrosine kinase Homo sapiens
2 Mutations in PLCgamma, a substrate of the tyrosine kinase BTK, are often found in patients who develop resistance to the BTK inhibitor Ibrutinib. ibrutinib Bruton tyrosine kinase Homo sapiens
3 Mutations in PLCgamma, a substrate of the tyrosine kinase BTK, are often found in patients who develop resistance to the BTK inhibitor Ibrutinib. ibrutinib Bruton tyrosine kinase Homo sapiens