Pub. Date : 2021 Dec 11
PMID : 34934478
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The fatty acid site is coupled to functional motifs in the SARS-CoV-2 spike protein and modulates spike allosteric behaviour. | Fatty Acids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 2 | The fatty acid site is coupled to functional motifs in the SARS-CoV-2 spike protein and modulates spike allosteric behaviour. | Fatty Acids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 3 | Recently, a fatty acid binding site was identified in the spike (Toelzer et al. | Fatty Acids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 4 | Here, dynamical-nonequilibrium molecular dynamics simulations reveal that this fatty acid site is coupled to functionally relevant regions of the spike, some of them far from the fatty acid binding pocket. | Fatty Acids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 5 | Here, dynamical-nonequilibrium molecular dynamics simulations reveal that this fatty acid site is coupled to functionally relevant regions of the spike, some of them far from the fatty acid binding pocket. | Fatty Acids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| 6 | Removal of a ligand from the fatty acid binding site significantly affects the dynamics of distant, functionally important regions of the spike, including the receptor-binding motif, furin cleavage site and fusion-peptide-adjacent regions. | Fatty Acids | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |