Title : Biochemical properties of human urinary megakaryocyte colony-stimulating factor and erythropoietin: the role of sulfhydryl groups and disulfide bonds.

Pub. Date : 1986

PMID : 3492399






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Reduction-carboxymethylation and reduction-mercuration resulted in complete loss of Meg-CSF and Epo activities, suggesting that one of the essential chemical groups of Meg-CSF and Epo is a disulfide bond. Disulfides erythropoietin Homo sapiens
2 Reduction-carboxymethylation and reduction-mercuration resulted in complete loss of Meg-CSF and Epo activities, suggesting that one of the essential chemical groups of Meg-CSF and Epo is a disulfide bond. Disulfides erythropoietin Homo sapiens
3 Reduction of disulfide bonds at neutral pH revealed that Meg-CSF is less susceptible to reduction than Epo. Disulfides erythropoietin Homo sapiens