Title : Recombinant human interleukin 1 alpha and beta stimulate mouse osteoblast-like cells (MC3T3-E1) to produce macrophage-colony stimulating activity and prostaglandin E2.

Pub. Date : 1986 Nov 26

PMID : 3492202






1 Functional Relationships(s)
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1 These results suggest that bone resorption induced by IL-1s is at least in part mediated by PGE2 produced by osteoblasts, and that M-CSA produced by osteoblasts may synergistically potentiate bone resorption by recruiting osteoclast precursors. Dinoprostone interleukin 1 complex Mus musculus