Pub. Date : 2021 Summer
PMID : 34903998
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lapachol-Induced Upregulation of Sirt1/Sirt3 is linked with Improved Skin Wound Healing in Alloxan-induced Diabetic Mice. | lapachol | sirtuin 1 | Mus musculus |
| 2 | Lapachol treatment was found to enhance the expression of sirt1/sirt3 and other proteins involved in cell migration and blood vessel formation. | lapachol | sirtuin 1 | Mus musculus |
| 3 | In summary, our findings suggest that lapachol promotes efficient wound healing in a diabetic mouse model by increasing the expression of sirt1 and sirt3 and other proteins related to wound repair and skin regeneration including alpha-PAK, RAC1/CDC42, VEGF and growth factors viz PDGF and VEGF. | lapachol | sirtuin 1 | Mus musculus |