Pub. Date : 1986
PMID : 3490132
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Drug interactions with macrolide antibiotics: specificity of pseudo-suicide inhibition and induction of cytochrome P-450. | macrolide antibiotics | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 2 | Macrolide antibiotics like Erythromycin and Tri-acetyl oleandomycin (TAO) are metabolized to nitrosoderivatives which cause inactivation of Cytochrome P-450 by forming stable complex with the Iron of the hemoporphyrin. | macrolide antibiotics | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |