Title : BTK-inhibitor drug covalent binding to lysine in human serum albumin using LC-MS/MS.

Pub. Date : 2022 Feb

PMID : 34896750






1 Functional Relationships(s)
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1 In this study, seven BTK-inhibitor drugs containing acrylamide warheads were incubated with human serum albumin (HSA) and analyzed using an LC-MS/MS peptide mapping approach to determine the amino acid sites of drug covalent binding. Acrylamide Bruton tyrosine kinase Homo sapiens