Title : Calcium handling genes are regulated by promoter DNA methylation in colorectal cancer cells.

Pub. Date : 2022 Jan 15

PMID : 34896109






1 Functional Relationships(s)
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1 Therefore, we measured the expression of six gene families involved in calcium regulation (ATP2A, ITPR, ORAI, RyR, STIM, and TRPC) in a colorectal cancer cell model, HCT116, with either genetic (Double Knock-out/DKO) or pharmacological (5-aza-2"-deoxycytidine/DAC) inhibition of DNA methyltransferases. Calcium ryanodine receptor 2 Homo sapiens