Title : REC8 enhances stemness and promotes metastasis of colorectal cancer through BTK/Akt/β-catenin signaling pathway.

Pub. Date : 2022 Jan

PMID : 34890967






1 Functional Relationships(s)
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1 Inhibition of BTK by ibrutinib not only suppressed the migration and invasion-promoting ability, but also declined the increased expression of p-BTK, p-Akt, beta-catenin, and CSC markers upon REC8 overexpression. ibrutinib AKT serine/threonine kinase 1 Homo sapiens