Title : Loss of peptidase D binding restores the tumor suppressor functions of oncogenic p53 mutants.

Pub. Date : 2021 Dec 8

PMID : 34880421






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Once freed from PEPD, p53 mutants undergo multiple posttranslational modifications, especially lysine 373 acetylation, which cause them to refold and regain tumor suppressor activities that are typically displayed by p53. Lysine tumor protein p53 Homo sapiens
2 Once freed from PEPD, p53 mutants undergo multiple posttranslational modifications, especially lysine 373 acetylation, which cause them to refold and regain tumor suppressor activities that are typically displayed by p53. Lysine tumor protein p53 Homo sapiens