Title : Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling.

Pub. Date : 2022 Jan

PMID : 34862975






1 Functional Relationships(s)
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1 In mice feed a HFD, the treatment with obeticholic acid, a clinical stage FXR agonist, failed to improve the liver histopathology while reduced Cyp7a1 and Cyp8b1 genes expression and bile acids synthesis and excretion. obeticholic acid nuclear receptor subfamily 1, group H, member 4 Mus musculus