Pub. Date : 2021 Nov 29
PMID : 34856328
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Up-regulation of VSIG4 alleviates kidney transplantation-associated acute kidney injury through suppressing inflammation and ROS via regulation of AKT signaling. | Reactive Oxygen Species | V-set and immunoglobulin domain containing 4 | Mus musculus |
| 2 | Oxidative stress and reactive oxygen species (ROS) accumulation in renal tissues were also mitigated by exogenous VSIG4 in CI/KT mice through improving nuclear factor-erythroid 2 related factor 2 (Nrf2) nuclear expression. | Reactive Oxygen Species | V-set and immunoglobulin domain containing 4 | Mus musculus |
| 3 | Oxidative stress and reactive oxygen species (ROS) accumulation in renal tissues were also mitigated by exogenous VSIG4 in CI/KT mice through improving nuclear factor-erythroid 2 related factor 2 (Nrf2) nuclear expression. | Reactive Oxygen Species | V-set and immunoglobulin domain containing 4 | Mus musculus |
| 4 | The inhibitory effects of VSIG4 on inflammation, ROS generation and cell death were confirmed in OGD/R-treated macrophages, which further ameliorated oxidative damage and apoptosis in podocytes. | Reactive Oxygen Species | V-set and immunoglobulin domain containing 4 | Mus musculus |