Title : KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs.

Pub. Date : 2022 Mar 1

PMID : 34853079






2 Functional Relationships(s)
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1 We show that KAT6A is the initiator of a newly-described transcriptional control module in which KAT6A-catalyzed promoter H3K9ac is bound by the acetyllysine reader ENL, which in turn cooperates with a network of chromatin factors to induce transcriptional elongation. N-epsilon-Acetyl-L-lysine lysine acetyltransferase 6A Homo sapiens
2 We show that KAT6A is the initiator of a newly-described transcriptional control module in which KAT6A-catalyzed promoter H3K9ac is bound by the acetyllysine reader ENL, which in turn cooperates with a network of chromatin factors to induce transcriptional elongation. N-epsilon-Acetyl-L-lysine lysine acetyltransferase 6A Homo sapiens