Title : CETP-inhibitors: from HDL-C to LDL-C lowering agents?

Pub. Date : 2021 Nov 26

PMID : 34849601






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Whereas first-generation CETP inhibitors (torcetrapib, dalcetrapib) were mainly raising HDL-C or had off-target effects, next generation CETP inhibitors (anacetrapib, evacetrapib) were also effective in reducing LDL-C and apoB and have been proven safe. anacetrapib cholesteryl ester transfer protein Homo sapiens
2 Anacetrapib was the first CETP inhibitor to be proven effective in reducing ASCVD risk. anacetrapib cholesteryl ester transfer protein Homo sapiens