Pub. Date : 2021 Nov 30
PMID : 34846077
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Terbutaline attenuates LPS-induced injury of pulmonary microvascular endothelial cells by cAMP/Epac signaling. | Terbutaline | Rap guanine nucleotide exchange factor 3 | Homo sapiens |
| 2 | This study is intended to explore whether terbutaline can alleviate LPS-induced human pulmonary microvascular endothelial cell (HPMVEC) injury through cAMP/Epac signaling. | Terbutaline | Rap guanine nucleotide exchange factor 3 | Homo sapiens |
| 3 | The levels of both cAMP and Epac reduced by LPS was concentration-dependently increased by terbutaline. | Terbutaline | Rap guanine nucleotide exchange factor 3 | Homo sapiens |
| 4 | The beneficial effects of terbutaline on alleviating the inflammation and apoptosis in HPMVECs injured by LPS are mediated by cAMP/Epac signaling, and this evidence would demonstrate the potential of terbutaline in the treatment of ALI. | Terbutaline | Rap guanine nucleotide exchange factor 3 | Homo sapiens |