Title : The potential role of c-MYC and polyamine metabolism in multiple drug resistance in bladder cancer investigated by metabonomics.

Pub. Date : 2022 Jan

PMID : 34843906






3 Functional Relationships(s)
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1 Subsequent experiments further confirmed that ornithine decarboxylase (ODC1) and spermidine synthase (SRM), the key enzymes involved in the synthesis of these compounds, also showed a stable low expression in T24/THP. pirarubicin spermidine synthase Homo sapiens
2 Subsequent experiments further confirmed that ornithine decarboxylase (ODC1) and spermidine synthase (SRM), the key enzymes involved in the synthesis of these compounds, also showed a stable low expression in T24/THP. pirarubicin spermidine synthase Homo sapiens
3 In addition, c-MYC could not only regulate the expression levels of ODC1 and SRM but also influence drug resistance in T24/THP. pirarubicin spermidine synthase Homo sapiens