Title : Abundance of Nef and p-Tau217 in Brains of Individuals Diagnosed with HIV-Associated Neurocognitive Disorders Correlate with Disease Severance.

Pub. Date : 2022 Feb

PMID : 34843091






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Previous studies suggested that HIV-1 Nef may contribute to HAND by inhibiting cholesterol efflux, increasing the abundance of lipid rafts, and affecting their functionality. Cholesterol S100 calcium binding protein B Homo sapiens
2 These results highlight the contribution of Nef and Nef-dependent impairment of cholesterol efflux to HAND pathogenesis and support a connection between the pathogenesis of HAND and Alzheimer"s disease. Cholesterol S100 calcium binding protein B Homo sapiens
3 These results highlight the contribution of Nef and Nef-dependent impairment of cholesterol efflux to HAND pathogenesis and support a connection between the pathogenesis of HAND and Alzheimer"s disease. Cholesterol S100 calcium binding protein B Homo sapiens