Title : CD47 interactions with exportin-1 limit the targeting of m7G-modified RNAs to extracellular vesicles.

Pub. Date : 2021 Nov 29

PMID : 34841476






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Interaction with CD47 was inhibited following alkylation of exportin-1 at Cys528 by its covalent inhibitor leptomycin B. leptomycin B exportin 1 Homo sapiens
2 Leptomycin B increased levels of m7G-modified RNAs, and their association with exportin-1 in EVs released from wild type but not CD47-deficient cells. leptomycin B exportin 1 Homo sapiens