Title : Mitochondria-Mediated Apoptosis of HCC Cells Triggered by Knockdown of Glutamate Dehydrogenase 1: Perspective for Its Inhibition through Quercetin and Permethylated Anigopreissin A.

Pub. Date : 2021 Nov 11

PMID : 34829892






1 Functional Relationships(s)
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Protein Name
Organism
1 GDH1 function may be relevant in cancer cells (or HCC) to drive the glutamine catabolism from L-glutamate towards the synthesis of alpha-ketoglutarate (alpha-KG), thus supplying key tricarboxylic acid cycle (TCA cycle) metabolites. Tricarboxylic Acids glutamate dehydrogenase 1 Homo sapiens