Title : Nox2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis.

Pub. Date : 2021 Oct 22

PMID : 34829531






3 Functional Relationships(s)
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1 Mice were either fed a standard diet or Western diet (WD) to study a possible interaction between NOX2-derived ROS and LDL. Reactive Oxygen Species cytochrome b-245, beta polypeptide Mus musculus
2 Nox2-/- macrophages produced basal levels of ROS but were unable to increase ROS production in response to the alarmin S100A8 or the phorbol ester PMA. Reactive Oxygen Species cytochrome b-245, beta polypeptide Mus musculus
3 These results suggest that NOX2-derived ROS are involved in CiOA development. Reactive Oxygen Species cytochrome b-245, beta polypeptide Mus musculus