Pub. Date : 2021 Oct 22
PMID : 34822470
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Act V-induced apoptosis was characterized by mitochondrial dysfunction, with loss of mitochondria membrane potential (MMP) and cytochrome c release, which then activated cleaved caspase-9, cleaved caspase-3, and cleaved PARP, revealing that it was related to the mitochondrial pathway, and the apoptotic trendency can be reversed by caspase inhibitor Z-VAD-FMK. | benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone | cytochrome c, somatic | Homo sapiens |