Title : Phytonutrient Inhibitors of SARS-CoV-2/NSP5-Encoded Main Protease (Mpro) Autocleavage Enzyme Critical for COVID-19 Pathogenesis.

Pub. Date : 2021 Nov 25

PMID : 34821532






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Quercetin binding to Mpro altered the thermostability of the viral protein through redox-based mechanism and inhibited the viral enzymatic activity. Quercetin NEWENTRY Severe acute respiratory syndrome-related coronavirus
2 Interaction of quercetin-derivatives with the Mpro seem to be influenced by the 7-OH group and the acetoxylation of sugar moiety on the ligand molecule. Quercetin NEWENTRY Severe acute respiratory syndrome-related coronavirus