Title : Drug connectivity mapping and functional analysis reveal therapeutic small molecules that differentially modulate myelination.

Pub. Date : 2022 Jan

PMID : 34813998






1 Functional Relationships(s)
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1 Notably, next generation pharmacogenomic analysis identified the PI3K/Akt modulator LY294002 as the most highly ranked small molecule with both pro- and anti-oligodendroglial concentration-dependent effects. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one AKT serine/threonine kinase 1 Homo sapiens