Title : Aloin alleviates pathological cardiac hypertrophy via modulation of the oxidative and fibrotic response.

Pub. Date : 2022 Jan 1

PMID : 34801516






1 Functional Relationships(s)
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1 Mechanistically, aloin attenuated ISO-induced fibrosis via inhibition of the levels of collagen I, alpha-smooth muscle actin (alpha-SMA), fibronectin, transforming growth factor-beta (TGF-beta) and pSmad2/3 proteins in the heart. Isoproterenol actin gamma 2, smooth muscle Rattus norvegicus