Title : Novel combination therapy of prostate cancer cells with arsenic trioxide and flutamide: An in-vitro study.

Pub. Date : 2022 Feb

PMID : 34800879






1 Functional Relationships(s)
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1 Generally, both cell lines treated with the combination of Flutamide and ATO showed a decrease in expression of KLK2, angiogenesis genes (VEGFA and VEGFC), and apoptosis gene (Bcl2), and an increase in expression of E-cadherin and P53 genes; however, contradictory findings were found regarding SNAIL expression in LNCaP and PC3 cells. Arsenic Trioxide vascular endothelial growth factor C Homo sapiens