Pub. Date : 2021
PMID : 34790046
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Long noncoding RNA CEBPA-DT promotes cisplatin chemo-resistance through CEBPA/BCL2 mediated apoptosis in oral squamous cellular cancer. | Cisplatin | CCAAT enhancer binding protein alpha | Homo sapiens |
| 2 | Here, we found that the expression of lncRNA CEBPA-DT/CEBPA/BCL2 was upregulated in cisplatin resistance OSCC cells (Cal27-CisR and HSC4-CisR) compared with their parental cells (Cal27 and HSC4). | Cisplatin | CCAAT enhancer binding protein alpha | Homo sapiens |
| 3 | Down-regulation of CEBPA-DT enhances cisplatin sensitivity, facilitates cell apoptosis in cisplatin-resistant OSCC cells. | Cisplatin | CCAAT enhancer binding protein alpha | Homo sapiens |
| 4 | Down-regulation of CEBPA-DT enhances cisplatin sensitivity, facilitates cell apoptosis in cisplatin-resistant OSCC cells. | Cisplatin | CCAAT enhancer binding protein alpha | Homo sapiens |
| 5 | In addition, we identified that CEBPA-DT regulates cisplatin chemosensitivity through CEBPA/BCL2-mediated cell apoptosis. | Cisplatin | CCAAT enhancer binding protein alpha | Homo sapiens |
| 6 | In addition, we identified that CEBPA-DT regulates cisplatin chemosensitivity through CEBPA/BCL2-mediated cell apoptosis. | Cisplatin | CCAAT enhancer binding protein alpha | Homo sapiens |
| 7 | Knockdown of CEBPA and BCL2 could alleviate the increasement of cisplatin resistance induced by CEBPA-DT overexpression. | Cisplatin | CCAAT enhancer binding protein alpha | Homo sapiens |
| 8 | Our findings indicate that downregulation of lncRNA CEBPA-DT may be a potential therapy to overcome cisplatin resistance in OSCC. | Cisplatin | CCAAT enhancer binding protein alpha | Homo sapiens |