Pub. Date : 2021 Dec
PMID : 34784434
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Previous studies have postulated that retinoic acid (RA), an active metabolite of vitamin A and high-affinity ligand for RA receptor (RAR), is reduced in airway inflammatory condition and contributes to multiple features of asthma including airway hyperresponsiveness and excessive accumulation of airway smooth muscle (ASM) cells. | Tretinoin | H19 imprinted maternally expressed transcript | Homo sapiens |
| 2 | Previous studies have postulated that retinoic acid (RA), an active metabolite of vitamin A and high-affinity ligand for RA receptor (RAR), is reduced in airway inflammatory condition and contributes to multiple features of asthma including airway hyperresponsiveness and excessive accumulation of airway smooth muscle (ASM) cells. | Tretinoin | H19 imprinted maternally expressed transcript | Homo sapiens |
| 3 | Further, basal RA levels and RA biosynthetic capabilities were decreased in asthmatic human ASM cells. | Tretinoin | H19 imprinted maternally expressed transcript | Homo sapiens |
| 4 | Further, basal RA levels and RA biosynthetic capabilities were decreased in asthmatic human ASM cells. | Tretinoin | H19 imprinted maternally expressed transcript | Homo sapiens |
| 5 | Treatment of human ASM cells with all-trans RA (ATRA) or the RARgamma-specific agonist (CD1530) resulted in the inhibition of mitogen-induced cell proliferation and AP-1-dependent transcription. | Tretinoin | H19 imprinted maternally expressed transcript | Homo sapiens |
| 6 | Treatment of human ASM cells with all-trans RA (ATRA) or the RARgamma-specific agonist (CD1530) resulted in the inhibition of mitogen-induced cell proliferation and AP-1-dependent transcription. | Tretinoin | H19 imprinted maternally expressed transcript | Homo sapiens |